SWOG clinical trial number
CTSU/A041202
A Randomized Phase III Study of Bendamustine plus Rituximab versus Ibrutinib plus Rituximab versus Ibrutinib Alone in Older Patients (>/= 65 Years of Age) with Chronic Lymphocytic Leukemia(CLL)
Closed
Phase
Abbreviated Title
Rand PIII Bendamustine/Rituximab vs. Ibrutinib/Rituximab vs. Ibrutinib for Untreated AML >/= 65
Status Notes
EFFECTIVE MONDAY, May 16, 2016 at 4:30 pm ET, A041202 will permanently close to new patient registration (Step 1).
Patients on treatment should continue to be treated and followed as required per protocol. Patients on Arm 1 who progress and who wish to crossover to receive ibrutinib alone will still be able to do so. Re-registration (Step 2) will remain open for crossover patients.
A registration closure notice will be included in the May 1, 2016 Alliance protocol posting and on the Alliance A041202 study page on the CTSU Web site thereafter.
Effective 12/28/15, A041202 permanently closed to new patient pre-registration (Step 0).
Questions may be directed to Samantha Sublett at ssublett@uchicago.edu or 773-834-4091
Patients on treatment should continue to be treated and followed as required per protocol. Patients on Arm 1 who progress and who wish to crossover to receive ibrutinib alone will still be able to do so. Re-registration (Step 2) will remain open for crossover patients.
A registration closure notice will be included in the May 1, 2016 Alliance protocol posting and on the Alliance A041202 study page on the CTSU Web site thereafter.
Effective 12/28/15, A041202 permanently closed to new patient pre-registration (Step 0).
Questions may be directed to Samantha Sublett at ssublett@uchicago.edu or 773-834-4091
Activated
12/15/2013
Closed
12/28/2015
Participants
Research committees
Leukemia
Treatment
Rituximab
Bendamustine
Ibrutinib
Eligibility Criteria Expand/Collapse
SWOG has endorsed this study through the Cancer Trials Support Unit (CTSU) of the National Cancer Institute.
Please contact the CTSU directly by phone (888/823-5923) or on the CTSU website (http://www.ctsu.org/) for more information and registration procedures.
Please contact the CTSU directly by phone (888/823-5923) or on the CTSU website (http://www.ctsu.org/) for more information and registration procedures.
Publication Information Expand/Collapse
2024
2023
2021
PMid: PMID34274940 | PMC number: PMC8744070
2018
Ibrutinib Regimens versus Chemoimmunotherapy in Older Patients with Untreated CLL
PMid: PMID30501481 | PMC number: PMC6325637
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Research Committee(s)
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