SWOG clinical trial number
              CTSU/AALL1821
          A Phase 2 Study of Blinatumomab (NSC# 765986) in Combination with Nivolumab (NSC # 748726), a Checkpoint Inhibitor of PD-1, in B-ALL Patients Aged >/= 1 to < 31 Years Old with First Relapse
Open
      
        
  Abbreviated Title
              A Phase 2 Study of Blinatumomab (NSC# 765986) in Combination with Nivolumab (NSC # 748726), a Checkpoint Inhibitor of PD-1, in B-ALL Patients Aged >/= 1 to < 31 Years Old with First Relapse<br />
          Status Notes
              This study is active in SWOG effective 4/1/21.
          Activated
              12/04/2020
          Participants
  
                          
      ALL NATIONAL CLINICAL TRIALS NETWORK MEMBERS LISTED ON TITLE PAGE
      
  
    Research committees
Leukemia
Treatment
                                
      Blinatumomab
                        
      Nivolumab
      
      
  
    Eligibility Criteria Expand/Collapse
      SWOG is participating in this study through the Cancer Trials Support Unit (CTSU) of the National Cancer Institute.
      
  
    Other Clinical Trials
SWOG Clinical Trial Number
              CTSU/A042001
          A Randomized Phase II Study Comparing Inotuzumab Plus Chemotherapy Versus Standard Chemotherapy in Older Adults with Philadelphia-Chromosome-Negative B-Cell Acute Lymphoblastic Leukemia
Research Committee(s)
      
            Leukemia
Activated
              02/27/2023
          Open
      
  Phase
              SWOG Clinical Trial Number
              S1925
          A Randomized, Phase III Study of Early Intervention with Venetoclax and Obinutuzumab versus Delayed Therapy with Venetoclax and Obinutuzumab in Newly Diagnosed Asymptomatic High-Risk Patients with Chronic Lymphocytic Leukemia (CLL): EVOLVE CLL Study.
Research Committee(s)
      
            Leukemia
Lymphoma
Symptom Control and Quality of Life
Activated
              12/14/2020
          Accrual
  
                          
      62%
      
  
    Open
      
  Phase
              SWOG Clinical Trial Number
              CTSU/AALL1821
          A Phase 2 Study of Blinatumomab (NSC# 765986) in Combination with Nivolumab (NSC # 748726), a Checkpoint Inhibitor of PD-1, in B-ALL Patients Aged >/= 1 to < 31 Years Old with First Relapse
Research Committee(s)
      
            Leukemia
Activated
              12/04/2020
          Open
      
        
  