Trials Open to Patients

Thank you for your interest in clinical trials! Every improvement in cancer treatment comes out of a clinical trial. Your participation moves cancer medicine forward.

Learn More About Our Trials

Bladder Cancer

Adding the New Drug Eribulin to Gemcitabine Chemotherapy for Urothelial Bladder Cancer That Has Spread

Breast Cancer

Adding Durvalumab to Usual Chemotherapy for People with Early-Stage Breast Cancer and MammaPrint High 2 Test Results

Breast Cancer

Monitoring Symptoms to Help Women Keep Taking Hormone Therapy for Early-Stage Breast Cancer

Breast Cancer

Testing Shorter Chemo-Immunotherapy Without Anthracycline Drugs for Early-Stage Triple Negative Breast Cancer

Breast Cancer

Testing a New Approach to Monitoring Hormone-Positive, HER2-Negative Breast Cancer That Has Spread

Colorectal Cancer

Treatment Options for People with Advanced Small Bowel Cancer

Colorectal Cancer

Adding the Drug Nivolumab to Usual Treatment for Colorectal Cancer That Has a BRAF Gene Change

Esophageal Cancer
Gastric Cancer

Adding Nivolumab to Usual Treatment for People with Advanced Stomach or Esophageal Cancer

Kidney/Renal Cancer

Adding The Drug Atezolizumab to a Usual Treatment for Advanced Papillary Renal Cell Cancer

Leukemia

Comparing New Treatments for People with Newly Diagnosed Acute Myeloid Leukemia That Has an IDH2 Gene Change

Leukemia
Lymphoma

Testing the Drug OBI-3424 in People with T-Cell Acute Lymphoblastic Leukemia or T-Cell Lymphoblastic Lymphoma

Leukemia
Lymphoma

Testing Early Treatment for Patients with Chronic Lymphocytic Leukemia (CLL) or Small Lymphocytic Lymphoma (SLL)

Leukemia

Testing New Treatments for People with High-Risk Acute Myeloid Leukemia (AML) Who Have Not Started Treatment

Lung Cancer

Targeted Treatment for Advanced Non-Small Cell Lung Cancer that has a MET Exon 14 Skipping Gene Change

Lung Cancer

Combining Targeted Drugs for Advanced Non-Small Cell Lung Cancer That Has EGFR and MET Gene Changes

Lung Cancer

Adding Cemiplimab to Usual Treatment for People with Advanced Non-Small Cell Lung Cancer Who Had Previous Treatment with Platinum Chemotherapy and Immunotherapy

Lung Cancer

Immunotherapy After Surgery for People with No Remaining Cancer After Standard Treatment for Early-Stage Non-Small Cell Lung Cancer

Lung Cancer

Targeted Treatment for Advanced Non-Small Cell Lung Cancer that has Extra Copies of the MET Gene

Lung Cancer

Targeted Treatment for People with Advanced Non-Small Cell Lung Cancer

Lymphoma

Comparing Rituximab and Mosunetuzumab Drug Treatments for People Who Have Follicular Lymphoma with Low Tumor Burden

Lymphoma

Treatment After CAR T-Cell Therapy for People with Diffuse Large B-Cell or Grade 3B Follicular Lymphoma

Lymphoma

Adding the Drugs Tazemetostat or Zanubrutinib to Usual Treatment for Large B-Cell Lymphoma That Returned or Did Not Respond to Previous Treatment

Melanoma
Head & Neck Cancer

Testing Biomarkers and Immunotherapy Drugs for People with Advanced Melanoma or Squamous-Cell Head and Neck Cancer

Multiple Cancers

Cooling and Compression to Prevent Peripheral Neuropathy (Nerve Damage) During Chemotherapy

Multiple Cancers

A Study to Predict Which Patients Are at Greatest Risk for Side Effects from Immunotherapy Drugs

Myeloma

Comparing Drug Combinations for Newly Diagnosed Multiple Myeloma When a Stem Cell Transplant is Not a Medically Suitable Treatment

Myeloma

Comparing Dara-VCD and Stem Cell Transplant as Consolidation Treatment for People with Newly Diagnosed AL Amyloidosis

Pancreatic Cancer

Chemotherapy after Surgery for People With High-Risk Pancreatic Neuroendocrine Tumors

Pancreatic Cancer

Adding The Drug Pembrolizumab to Usual Treatment for People with Advanced Pancreatic Cancer and a BRCA Gene Change

Pancreatic Cancer

Lanreotide versus Placebo Before Surgery to Prevent a Surgical Complication Called a Pancreatic Fistula

Prostate Cancer

Combining Cabazitaxel and Carboplatin to Treat Castrate-Resistant Prostate Cancer: Could Testing for Aggressive Variant Prostate Cancer Help Guide Treatment?

Prostate Cancer

Carboplatin Chemotherapy Before Surgery For People With High-Risk Prostate Cancer and an Inherited BRCA1 or BRCA2 Gene Mutation

Waldenström’s Macroglobulinemia
Lymphoma

Combining the Drugs Venetoclax and Rituximab as a First Treatment for Waldenström’s Macroglobulinemia

To find out about all SWOG trial options available to you, as well as trials run by other groups, please call 1-800-4-CANCER.

You can also find other cancer clinical trials supported by the National Cancer Institute on the NCI clinical trials search page.