A Phase II Pilot Study of High-Dose 24 Hour Continuous Infusion 5-FU and Leucovorin and Low-Dose PALA in Patients with Pancreatic Adenocarcinoma

Closed

Phase

Accrual

86%

Published

Abbreviated Title

A Phase II Pilot Study of High-Dose 24 Hour Continuous Infusion 5-FU and Leucovorin and Low-Dose PALA in Patients with Pancreatic Adenocarcinoma

Activated

01/15/1993

Closed

08/01/1994

Publication Information Expand/Collapse

2014

Historical controls for metastatic pancreatic cancer: benchmarks for planning and analyzing single arm phase II trials

PA Philip;K Chansky;L Rubenstein;M Leblanc;L Seymour;SP Ivy;SR Alberts;PJ Catalano;J Crowley Clinical Cancer Research 20(16):4176-4185;

PMid: PMID24914040 | PMC number: PMC4296727

2004

A phase II study of high-dose 24 hour continuous infusion 5-FU and leucovorin and low-dose PALA for patients with advanced pancreatic adenocarcinoma: a Southwest Oncology Group study

RP Whitehead;J Benedetti;JL Abbruzzese;B Ardalan;JW Goodwin;SP Balcerzak;W Samlowski;HJ Lenz;JS Macdonald Investigational New Drugs 22:335-341